Tegretol

Indicated to manage seizure frequency, developed to alleviate abnormal electrical brain activity and to support neurological stability.

Strengths: 100 · 200 · 400mg

Neurology icon Neurology Carbamazepine icon Carbamazepine

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Medicine details

Conditions
Alternative names

Timonil

Therapeutic class

Antiepileptic

Pharmacological class

Dibenzazepine Derivative

Known off-label uses

bipolar disorder

Precautions and warnings

monitor for serious skin reactions; regular blood count monitoring

Minor side effects

dizziness; drowsiness; nausea

Moderate side effects

leukopenia; skin rash; ataxia

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Novartis

Onset Time

2–4 days

Duration

12–24 hours

Storage instructions

Store in a cool, dry place.

Drug interactions

grapefruit; oral contraceptives; warfarin

Age restrictions

Suitable for children and adults.

Contraindications

atrioventricular conduction block; history of bone marrow depression; porphyria; concurrent use of maois

Serious side effects

stevens-johnson syndrome — requires immediate medical attention; agranulocytosis — requires immediate medical attention; aplastic anaemia — requires immediate medical attention

Patient summary

Indicated to manage seizure frequency, developed to alleviate abnormal electrical brain activity and to support neurological stability.

Mechanism of action

Carbamazepine stabilizes nerve membranes by inhibiting voltage-gated sodium channels, which decreases the neuronal hyperexcitability and prevents the repetitive firing of seizures.

Pregnancy and breastfeeding

Pregnancy: Associated with birth defects; consult specialist. Breastfeeding: Not recommended.

Tegretol

Indicated to manage seizure frequency, developed to alleviate abnormal electrical brain activity and to support neurological stability.

Editorial Notes

  • Active ingredient(s): Carbamazepine
  • Listed indication(s): Epilepsy, Trigeminal Neuralgia

Usually available as

  • 360 tablets - 100 mg574-100-mg-4262
  • 360 tablets - 200 mg574-200-mg-4268
  • 120 tablets - 400 mg574-400-mg-4272