Depakene
Formulated to manage epilepsy and bipolar disorder, this medication is indicated to support the control of seizures and is utilized to mitigate mood fluctuations.
Strengths: 250 · 750mg
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Medicine details
- Alternative names
Epilim; Depakote
- Therapeutic class
Antiepileptic
- Pharmacological class
Valproate
- Contraindications
hepatic impairment; urea cycle disorders; pregnancy; porphyria
- Minor side effects
nausea; tremor; dizziness; somnolence
- Moderate side effects
weight gain; hair loss; oedema
- Dosage forms
Capsule, soft
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Abbott
- Onset Time
1–4 weeks
- Duration
24 hours
- Storage instructions
Store at room temperature.
- Drug interactions
alcohol; phenobarbital; carbamazepine; rifampicin
- Age restrictions
Use with caution in children.
Precautions and warnings
monitor liver function; monitor for signs of depression; avoid rapid discontinuation
Serious side effects
hepatotoxicity — requires immediate medical attention; pancreatitis — requires immediate medical attention; thrombocytopenia — requires immediate medical attention
Patient summary
Formulated to manage epilepsy and bipolar disorder, this medication is indicated to support the control of seizures and is utilized to mitigate mood fluctuations.
Mechanism of action
Valproic acid increases the concentration of gamma-aminobutyric acid (GABA) in the brain, thereby inhibiting excessive neuronal activity and reducing seizure frequency.
Pregnancy and breastfeeding
Pregnancy: Contraindicated; high risk of malformations. Breastfeeding: Consult a physician.
Depakene
Formulated to manage epilepsy and bipolar disorder, this medication is indicated to support the control of seizures and is utilized to mitigate mood fluctuations.
Editorial Notes
- Active ingredient(s): Valproic Acid
- Listed indication(s): Epilepsy, Bipolar Disorder, Migraine Prophylaxis
Usually available as
- 60 capsules - 250 mg1097-250-mg-18201
- 30 capsules - 750 mg1097-750-mg-18203