Mysoline
Utilized to target uncontrolled seizure activity, this anticonvulsant is indicated to alleviate the frequency and severity of various epilepsy types.
Strengths: 250mg
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Medicine details
- Conditions
- Therapeutic class
Antiepileptic
- Pharmacological class
Barbiturate
- Known off-label uses
essential tremor
- Contraindications
hypersensitivity to primidone; porphyria
- Precautions and warnings
avoid abrupt withdrawal; may cause drowsiness; monitor blood counts periodically
- Minor side effects
sedation; dizziness; fatigue; ataxia
- Moderate side effects
nystagmus; lethargy; confusion
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Concordia International
- Onset Time
1–2 hours
- Duration
12–24 hours
- Storage instructions
Store in dry conditions at room temperature.
- Drug interactions
alcohol; cns depressants; valproate
- Age restrictions
Use with caution in children.
Serious side effects
megaloblastic anaemia — requires immediate medical attention; blood dyscrasias — requires immediate medical attention
Patient summary
Utilized to target uncontrolled seizure activity, this anticonvulsant is indicated to alleviate the frequency and severity of various epilepsy types.
Mechanism of action
Primidone is metabolized into phenobarbital and phenylethylmalonamide (PEMA), both of which possess anticonvulsant properties. They enhance GABA-mediated inhibition, suppressing excessive neuronal firing.
Pregnancy and breastfeeding
Pregnancy: Use with extreme caution. Breastfeeding: May cause sedation in infants.
Mysoline
Utilized to target uncontrolled seizure activity, this anticonvulsant is indicated to alleviate the frequency and severity of various epilepsy types.
Editorial Notes
- Active ingredient(s): Primidone
- Listed indication(s): Epilepsy
Available option
- 120 tablets - 250 mg145-250-mg-3655