Lamictal

Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.

Strengths: 25 · 50 · 100 · 200mg

Medicine details

Therapeutic class

Antiepileptic

Pharmacological class

Phenyltriazine

Contraindications

hypersensitivity to lamotrigine

Minor side effects

headache; dizziness; nausea; somnolence

Moderate side effects

diplopia; blurred vision; ataxia

Dosage forms

Tablet; Dispersible tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

GSK

Onset Time

1–3 hours

Duration

24–36 hours

Storage instructions

Store at room temperature in a dry place.

Drug interactions

valproate; carbamazepine; phenytoin; hormonal contraceptives

Age restrictions

Not recommended for children under 2 years.

Precautions and warnings

risk of serious skin rashes; monitor for signs of hypersensitivity; advise avoiding abrupt discontinuation

Serious side effects

stevens-johnson syndrome — requires immediate medical attention; toxic epidermal necrolysis — requires immediate medical attention; haemophagocytic lymphohistiocytosis — requires immediate medical attention

Patient summary

Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.

Mechanism of action

Lamotrigine stabilizes neuronal membranes by inhibiting voltage-gated sodium channels, which limits the release of excitatory neurotransmitters like glutamate. This mechanism supports control of seizure thresholds and mood stabilisation.

Pregnancy and breastfeeding

Pregnancy: Use with caution as risks to the foetus are currently being evaluated. Breastfeeding: Small amounts pass into breast milk; monitoring is recommended.

Lamictal

Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.

Editorial Notes

  • Active ingredient(s): Lamotrigine
  • Listed indication(s): Epilepsy, Bipolar Disorder

Usually available as

  • 120 tablets - 25 mg137-25-mg-3321
  • 90 tablets - 50 mg137-50-mg-3326
  • 60 tablets - 100 mg137-100-mg-3330