Lamictal
Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.
Strengths: 25 · 50 · 100 · 200mg
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Medicine details
- Conditions
- Therapeutic class
Antiepileptic
- Pharmacological class
Phenyltriazine
- Contraindications
hypersensitivity to lamotrigine
- Minor side effects
headache; dizziness; nausea; somnolence
- Moderate side effects
diplopia; blurred vision; ataxia
- Dosage forms
Tablet; Dispersible tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
GSK
- Onset Time
1–3 hours
- Duration
24–36 hours
- Storage instructions
Store at room temperature in a dry place.
- Drug interactions
valproate; carbamazepine; phenytoin; hormonal contraceptives
- Age restrictions
Not recommended for children under 2 years.
Precautions and warnings
risk of serious skin rashes; monitor for signs of hypersensitivity; advise avoiding abrupt discontinuation
Serious side effects
stevens-johnson syndrome — requires immediate medical attention; toxic epidermal necrolysis — requires immediate medical attention; haemophagocytic lymphohistiocytosis — requires immediate medical attention
Patient summary
Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.
Mechanism of action
Lamotrigine stabilizes neuronal membranes by inhibiting voltage-gated sodium channels, which limits the release of excitatory neurotransmitters like glutamate. This mechanism supports control of seizure thresholds and mood stabilisation.
Pregnancy and breastfeeding
Pregnancy: Use with caution as risks to the foetus are currently being evaluated. Breastfeeding: Small amounts pass into breast milk; monitoring is recommended.
Lamictal
Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.
Editorial Notes
- Active ingredient(s): Lamotrigine
- Listed indication(s): Epilepsy, Bipolar Disorder
Usually available as
- 120 tablets - 25 mg137-25-mg-3321
- 90 tablets - 50 mg137-50-mg-3326
- 60 tablets - 100 mg137-100-mg-3330