Neurontin
Intended to alleviate chronic neuropathic pain and prevent seizures, utilized to support neurological stability and enhance quality of life.
Strengths: 100 · 300 · 400 · 600mg
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Medicine details
- Conditions
- Therapeutic class
Antiepileptic
- Pharmacological class
GABA analogue
- Known off-label uses
generalised anxiety disorder
- Contraindications
hypersensitivity to gabapentin
- Minor side effects
dizziness; somnolence; fatigue; nausea
- Moderate side effects
peripheral oedema; ataxia; tremor
- Dosage forms
Capsule, hard
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 weeks
- Duration
6–8 hours
- Storage instructions
Store at room temperature below 25°C.
- Drug interactions
Alcohol; antacids; morphine
- Age restrictions
Safe for use in children from 6 years for epilepsy.
- Pregnancy and breastfeeding
Use only if the potential benefit outweighs the risk to the foetus.
Precautions and warnings
may cause drowsiness; do not stop treatment abruptly; avoid driving or operating machinery if dizziness occurs
Serious side effects
respiratory depression — requires immediate medical attention; suicidal ideation — requires immediate medical attention; anaphylaxis — requires immediate medical attention
Patient summary
Intended to alleviate chronic neuropathic pain and prevent seizures, utilized to support neurological stability and enhance quality of life.
Mechanism of action
Gabapentin is a structural analogue of the neurotransmitter GABA, although it does not interact directly with GABA receptors. It binds to the alpha-2-delta subunit of voltage-gated calcium channels, which modulates the release of excitatory neurotransmitters.
Neurontin
Intended to alleviate chronic neuropathic pain and prevent seizures, utilized to support neurological stability and enhance quality of life.
Editorial Notes
- Active ingredient(s): Gabapentin
- Listed indication(s): Epilepsy, Neuropathic Pain
Usually available as
- 60 tablets - 300 mg223-300-mg-5078
- 60 tablets - 400 mg223-400-mg-5085
- 30 tablets - 600 mg223-600-mg-5090