Azathioprine Tablets
designed to address chronic inflammation to target immune system activity.
Strengths: 25 · 50mg
Where to Check Availability
Medicine details
- Alternative names
Imuran
- Therapeutic class
Immunosuppressant
- Pharmacological class
Purine analogue
- Known off-label uses
ulcerative colitis
- Contraindications
hypersensitivity; severe infection; severe hepatic impairment
- Precautions and warnings
monitor haematological counts regularly; avoid live vaccines
- Minor side effects
nausea; loss of appetite
- Moderate side effects
leukopenia; elevated liver enzymes
- Serious side effects
bone marrow suppression — requires immediate medical attention
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Patient summary
designed to address chronic inflammation to target immune system activity.
- Prescription status
POM
- Manufacturer
Aspen Pharma
- Onset Time
2–4 weeks
- Duration
constant
- Storage instructions
Store below 25°C, protect from light.
- Drug interactions
allopurinol; warfarin; ribavirin
- Age restrictions
Adjust dose for paediatric use.
- Pregnancy and breastfeeding
Pregnancy: avoid if possible. Breastfeeding: avoid, drug is excreted in milk.
Mechanism of action
Azathioprine acts as a purine antimetabolite, interfering with DNA and RNA synthesis, which inhibits the proliferation of cells involved in the immune response.
Azathioprine Tablets
designed to address chronic inflammation to target immune system activity.
Editorial Notes
- Active ingredient(s): Azathioprine
- Listed indication(s): Rheumatoid Arthritis, Crohn’s Disease, Transplant Rejection
Usually available as
- 120 tablets - 25 mg1345-25-mg-16243
- 90 tablets - 50 mg1345-50-mg-16236