Cyclosporine Capsules
Formulated to mitigate immune responses, utilized to support organ transplant maintenance.
Strengths: 25 · 50 · 100mg
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Medicine details
- Conditions
- Alternative names
Neoral; Sandimmun
- Therapeutic class
Immunosuppressant
- Pharmacological class
Calcineurin Inhibitor
- Contraindications
renal impairment; uncontrolled hypertension
- Precautions and warnings
monitor blood pressure; avoid excessive sun exposure
- Minor side effects
tremor; hypertrichosis
- Moderate side effects
renal dysfunction; hypertension
- Dosage forms
Capsule, soft
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Novartis
- Onset Time
3–7 days (steady state)
- Duration
Long-term usage
- Storage instructions
Store below 25°C.
- Drug interactions
grapefruit juice; st. john's wort
- Pregnancy and breastfeeding
Pregnancy: Use only if benefit justifies risk. Breastfeeding: Not recommended.
Serious side effects
nephrotoxicity — requires immediate medical attention; lymphoma — requires immediate medical attention
Patient summary
Formulated to mitigate immune responses, utilized to support organ transplant maintenance.
Mechanism of action
Cyclosporine inhibits calcineurin, a phosphatase involved in T-lymphocyte activation. By preventing the transcription of IL-2 and other cytokines, it suppresses the immune response necessary for transplant rejection.
Cyclosporine Capsules
Formulated to mitigate immune responses, utilized to support organ transplant maintenance.
Editorial Notes
- Active ingredient(s): Cyclosporine
- Listed indication(s): Transplant Rejection, Rheumatoid Arthritis
Usually available as
- 24 tablets - 25 mg1186-25-mg-14039
- 24 tablets - 50 mg1186-50-mg-14043
- 24 tablets - 100 mg1186-100-mg-14036