Azulfidine
Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.
Strengths: 500mg
Where to Check Availability
Medicine details
- Alternative names
Salazopyrin
- Therapeutic class
Disease-modifying antirheumatic drug (DMARD)
- Pharmacological class
Sulfonamide
- Minor side effects
headache; nausea; loss of appetite
- Moderate side effects
rash; fever; anaemia
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 weeks
- Duration
24 hours
- Storage instructions
Store at room temperature away from sunlight and moisture.
- Drug interactions
digoxin; folic acid
- Age restrictions
Use with caution in elderly patients.
Contraindications
hypersensitivity to sulfonamides or salicylates; intestinal or urinary obstruction; porphyria; severe hepatic or renal impairment
Precautions and warnings
maintain adequate fluid intake to prevent crystalluria; regular blood count monitoring is essential; may cause temporary orange discolouration of body fluids
Serious side effects
blood dyscrasias — requires immediate medical attention; stevens-johnson syndrome — requires immediate medical attention; hepatitis — requires immediate medical attention
Patient summary
Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.
Mechanism of action
The active substance exerts anti-inflammatory and immunomodulatory effects within the gastrointestinal tract and synovial joints by inhibiting prostaglandin synthesis and inflammatory mediator release.
Pregnancy and breastfeeding
Pregnancy: Consult a specialist; use only if benefit outweighs risk. Breastfeeding: Use with caution as it is excreted in breast milk.
Azulfidine
Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.
Editorial Notes
- Active ingredient(s): Sulfasalazine
- Listed indication(s): Rheumatoid Arthritis, Ulcerative Colitis, Crohn’s Disease
Available option
- 90 tablets - 500 mg648-500-mg-2202