Azulfidine

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

Strengths: 500mg

Medicine details

Alternative names

Salazopyrin

Therapeutic class

Disease-modifying antirheumatic drug (DMARD)

Pharmacological class

Sulfonamide

Minor side effects

headache; nausea; loss of appetite

Moderate side effects

rash; fever; anaemia

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

1–2 weeks

Duration

24 hours

Storage instructions

Store at room temperature away from sunlight and moisture.

Drug interactions

digoxin; folic acid

Age restrictions

Use with caution in elderly patients.

Contraindications

hypersensitivity to sulfonamides or salicylates; intestinal or urinary obstruction; porphyria; severe hepatic or renal impairment

Precautions and warnings

maintain adequate fluid intake to prevent crystalluria; regular blood count monitoring is essential; may cause temporary orange discolouration of body fluids

Serious side effects

blood dyscrasias — requires immediate medical attention; stevens-johnson syndrome — requires immediate medical attention; hepatitis — requires immediate medical attention

Patient summary

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

Mechanism of action

The active substance exerts anti-inflammatory and immunomodulatory effects within the gastrointestinal tract and synovial joints by inhibiting prostaglandin synthesis and inflammatory mediator release.

Pregnancy and breastfeeding

Pregnancy: Consult a specialist; use only if benefit outweighs risk. Breastfeeding: Use with caution as it is excreted in breast milk.

Azulfidine

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

Editorial Notes

  • Active ingredient(s): Sulfasalazine
  • Listed indication(s): Rheumatoid Arthritis, Ulcerative Colitis, Crohn’s Disease

Available option

  • 90 tablets - 500 mg648-500-mg-2202