Neoral

This medication is intended to support the immune system and is indicated to alleviate risks associated with organ transplant rejection.

Strengths: 25 · 100mg

Medicine details

Alternative names

Capimune

Therapeutic class

Immunosuppressant

Pharmacological class

Calcineurin inhibitor

Minor side effects

tremor; fatigue; nausea

Moderate side effects

hypertension; hirsutism; renal impairment

Dosage forms

Capsule, soft

Administration route

Oral use

Prescription status

POM

Manufacturer

Novartis

Onset Time

1–2 weeks

Duration

Continuous

Storage instructions

Store at room temperature below 25°C.

Drug interactions

grapefruit; st. john's wort; tacrolimus; ketoconazole

Age restrictions

Dose adjustment required for children.

Pregnancy and breastfeeding

Pregnancy: Use only if strictly necessary. Breastfeeding: Not recommended.

Contraindications

hypersensitivity to cyclosporine; uncontrolled hypertension; malignancy; impaired renal function

Precautions and warnings

requires regular monitoring of blood levels; avoid excessive sun exposure; do not substitute with generic cyclosporine without advice

Serious side effects

nephrotoxicity — requires immediate medical attention; skin malignancy — requires immediate medical attention

Patient summary

This medication is intended to support the immune system and is indicated to alleviate risks associated with organ transplant rejection.

Mechanism of action

Cyclosporine is a potent immunosuppressive agent that selectively inhibits the production and release of interleukin-2 by T-lymphocytes. This blocks the activation of T-cells, preventing the body from rejecting transplanted organs and suppressing autoimmune activity.

Neoral

This medication is intended to support the immune system and is indicated to alleviate risks associated with organ transplant rejection.

Editorial Notes

  • Active ingredient(s): Cyclosporine
  • Listed indication(s): Transplant Rejection, Rheumatoid Arthritis, Psoriasis

Usually available as

  • 20 tablets - 25 mg641-25-mg-3675
  • 20 tablets - 100 mg641-100-mg-1310