Imuran
Developed to target immune system activity, utilized to mitigate inflammation in autoimmune processes and to support transplant rejection prevention.
Strengths: 25 · 50mg
Where to Check Availability
Medicine details
- Therapeutic class
Immunosuppressant
- Pharmacological class
Purine Analogue
- Known off-label uses
crohn's disease
- Minor side effects
nausea; fatigue; infection
- Moderate side effects
leukopenia; thrombocytopenia; elevated liver enzymes
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Aspen Pharma
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store below 25°C in original packaging.
- Drug interactions
allopurinol; warfarin
- Age restrictions
Used in children and adults under specialist supervision.
Contraindications
hypersensitivity to azathioprine; severe infections; severe bone marrow suppression
Precautions and warnings
monitor full blood count; limit sun exposure due to skin cancer risk; report any signs of infection immediately
Serious side effects
bone marrow suppression — requires immediate medical attention; malignancy — requires immediate medical attention; pancreatitis — requires immediate medical attention
Patient summary
Developed to target immune system activity, utilized to mitigate inflammation in autoimmune processes and to support transplant rejection prevention.
Mechanism of action
Azathioprine is a purine analogue that interferes with DNA synthesis, thereby inhibiting the proliferation of rapidly dividing cells such as T-lymphocytes necessary for immune responses.
Pregnancy and breastfeeding
Pregnancy: Use only if benefits outweigh risks. Breastfeeding: Small amounts excreted; specialist advice required.
Imuran
Developed to target immune system activity, utilized to mitigate inflammation in autoimmune processes and to support transplant rejection prevention.
Editorial Notes
- Active ingredient(s): Azathioprine
- Listed indication(s): Transplant Rejection, Rheumatoid Arthritis, Systemic Lupus Erythematosus
Usually available as
- 120 tablets - 25 mg572-25-mg-3209
- 90 tablets - 50 mg572-50-mg-1193