Voriconazole Tablets
Formulated to target fungal pathogens and indicated to mitigate systemic fungal infections.
Strengths: 200mg
Where to Check Availability
Medicine details
- Alternative names
Vfend
- Therapeutic class
Triazole Antifungal
- Pharmacological class
Triazole
- Minor side effects
nausea; rash; vomiting; diarrhoea
- Moderate side effects
visual disturbances; elevated liver enzymes; peripheral oedema; headache
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
1–2 hours
- Duration
12 hours
- Storage instructions
Store below 30°C in the original packaging.
- Drug interactions
rifampicin; phenytoin; carbamazepine
- Age restrictions
Not for children under two years.
- Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine; concurrent use of St. John's wort
Precautions and warnings
monitor liver function regularly; avoid prolonged sun exposure; monitor visual function if treatment is prolonged
Serious side effects
hepatitis — requires immediate medical attention; Stevens-Johnson syndrome — requires immediate medical attention; QT prolongation — requires immediate medical attention
Patient summary
Formulated to target fungal pathogens and indicated to mitigate systemic fungal infections.
Mechanism of action
Voriconazole acts by inhibiting the fungal cytochrome P450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis, resulting in membrane disruption.
Voriconazole Tablets
Formulated to target fungal pathogens and indicated to mitigate systemic fungal infections.
Editorial Notes
- Active ingredient(s): Voriconazole
- Listed indication(s): Invasive Aspergillosis, Candidemia, Oesophageal Candidiasis
Available option
- 4 tablets - 200 mg1257-200-mg-15002