Itraconazole Capsules
designed for candidiasis to target fungal growth.
Strengths: 100 · 200mg
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Medicine details
- Alternative names
Sporanox
- Therapeutic class
Antifungal
- Pharmacological class
Triazole Antifungal
- Known off-label uses
aspergillosis
- Minor side effects
nausea; diarrhoea; headache
- Moderate side effects
rash; elevated liver enzymes
- Dosage forms
Capsule, hard
- Administration route
Oral use
- Patient summary
designed for candidiasis to target fungal growth.
- Prescription status
POM
- Manufacturer
Janssen-Cilag
- Onset Time
2–4 weeks
- Duration
variable
- Storage instructions
Store in a dry place at room temperature.
- Drug interactions
atorvastatin; simvastatin; quetiapine
- Age restrictions
Use with caution in elderly and children.
- Pregnancy and breastfeeding
Avoid during pregnancy unless clearly necessary.
Contraindications
hypersensitivity to itraconazole; concomitant administration of certain statins; ventricular dysfunction
Precautions and warnings
monitor liver function in prolonged therapy; avoid in patients with history of heart failure
Serious side effects
hepatotoxicity — requires immediate medical attention; congestive heart failure — requires immediate medical attention
Mechanism of action
It works by inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, which disrupts ergosterol synthesis. This stops the growth of the cell membrane, providing a standard treatment for fungal infections.
Itraconazole Capsules
designed for candidiasis to target fungal growth.
Editorial Notes
- Active ingredient(s): Itraconazole
- Listed indication(s): Candidiasis, Pityriasis Versicolor, Dermatomycosis
Usually available as
- 120 capsules - 100 mg1106-100-mg-13332
- 60 capsules - 200 mg1106-200-mg-13337