Fluconazole Tablets
formulated to alleviate fungal growth and to address infections caused by susceptible fungi.
Strengths: 50 · 100 · 150 · 200 · 400mg
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Medicine details
- Alternative names
Diflucan
- Therapeutic class
Triazole Antifungal
- Pharmacological class
Antifungal
- Contraindications
hypersensitivity to azoles; concurrent use of terfenadine or cisapride
- Minor side effects
nausea; headache; abdominal pain; diarrhoea
- Moderate side effects
rash; elevated liver enzymes
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Various
- Onset Time
24–48 hours
- Duration
variable
- Storage instructions
Store at room temperature.
- Drug interactions
rifampicin; warfarin; phenytoin
- Age restrictions
Dosage adjusted for children based on weight.
Precautions and warnings
monitor liver function in patients with chronic systemic infections; risk of QT interval prolongation
Serious side effects
anaphylaxis — requires immediate medical attention; stevens-johnson syndrome — requires immediate medical attention; acute hepatic failure — requires immediate medical attention
Patient summary
formulated to alleviate fungal growth and to address infections caused by susceptible fungi.
Mechanism of action
Highly specific inhibitor of fungal cytochrome P450-dependent enzyme lanosterol 14-alpha-demethylase, which prevents the synthesis of ergosterol in fungal cell membranes.
Pregnancy and breastfeeding
Pregnancy: Avoid unless strictly indicated. Breastfeeding: Present in breast milk; consult your doctor.
Fluconazole Tablets
formulated to alleviate fungal growth and to address infections caused by susceptible fungi.
Editorial Notes
- Active ingredient(s): Fluconazole
- Listed indication(s): Candidiasis, Vaginal Candidiasis, Cryptococcal Meningitis
Usually available as
- 92 tablets - 50 mg482-50-mg-13824
- 60 tablets - 100 mg482-100-mg-13808
- 90 tablets - 150 mg482-150-mg-13814