Elavil

Designed for effective depressive symptoms management and utilized to support mood stability in patients.

Strengths: 10 · 25 · 50mg

Antidepressants icon Antidepressants Neurology icon Neurology Amitriptyline icon Amitriptyline

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Medicine details

Conditions
Alternative names

Tryptizol

Therapeutic class

Tricyclic Antidepressant (TCA)

Pharmacological class

TCA

Known off-label uses

tension-type headache

Minor side effects

dry mouth; sedation; dizziness; constipation

Moderate side effects

urinary retention; blurred vision; weight gain; tachycardia

Dosage forms

Tablet; Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

AstraZeneca

Onset Time

2–4 weeks

Duration

24 hours

Storage instructions

Store in a cool, dry place.

Drug interactions

Alcohol; MAO inhibitors; Cimetidine

Age restrictions

Not for use in children and adolescents.

Contraindications

recent myocardial infarction; heart block; arrhythmia; severe liver impairment; mania

Precautions and warnings

may impair ability to drive or operate machinery; use with caution in elderly patients; may affect blood sugar control

Serious side effects

cardiac arrhythmia — requires immediate medical attention; convulsions — requires immediate medical attention; paralytic ileus — requires immediate medical attention

Patient summary

Designed for effective depressive symptoms management and utilized to support mood stability in patients.

Mechanism of action

This medicine acts by increasing the concentration of neurotransmitters like serotonin and noradrenaline in the synaptic cleft by inhibiting their reuptake into nerve terminals, thereby enhancing mood and providing pain-relieving effects.

Pregnancy and breastfeeding

Pregnancy: Not recommended. Breastfeeding: Small amounts excreted in milk; monitor infant.

Elavil

Designed for effective depressive symptoms management and utilized to support mood stability in patients.

Editorial Notes

  • Active ingredient(s): Amitriptyline
  • Listed indication(s): Major Depressive Disorder, Neuropathic Pain, Migraine Prophylaxis

Usually available as

  • 360 tablets - 10 mg64-10-mg-2819
  • 270 tablets - 25 mg64-25-mg-2825
  • 180 tablets - 50 mg64-50-mg-2831