Hydroxychloroquine Tablets
developed to manage autoimmune symptoms and suppress inflammatory responses.
Strengths: 200 · 400mg
Where to Check Availability
Medicine details
- Alternative names
Plaquenil
- Therapeutic class
Antirheumatic
- Pharmacological class
Aminoquinoline
- Known off-label uses
dermatitis
- Contraindications
hypersensitivity to 4-aminoquinoline derivatives; pre-existing maculopathy
- Minor side effects
nausea; abdominal cramps
- Moderate side effects
headache; skin rash
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Patient summary
developed to manage autoimmune symptoms and suppress inflammatory responses.
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
4–12 weeks
- Duration
Long-term
- Storage instructions
No special storage conditions.
- Drug interactions
digoxin; tamoxifen
- Age restrictions
Not for paediatric use in autoimmune conditions.
- Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary. Breastfeeding: Consult a physician.
Precautions and warnings
regular eye examinations recommended; monitor blood glucose; use with caution in hepatic impairment
Serious side effects
retinopathy — requires immediate medical attention; cardiomyopathy — requires immediate medical attention; QT prolongation — requires immediate medical attention
Mechanism of action
Hydroxychloroquine exhibits anti-inflammatory and immunomodulatory properties by interfering with lysosomal activity and increasing the intracellular pH in antigen-presenting cells, which reduces the presentation of autoantigens.
Hydroxychloroquine Tablets
developed to manage autoimmune symptoms and suppress inflammatory responses.
Editorial Notes
- Active ingredient(s): Hydroxychloroquine
- Listed indication(s): Rheumatoid Arthritis, Systemic Lupus Erythematosus
Usually available as
- 120 tablets - 200 mg1046-200-mg-13344
- 120 tablets - 400 mg1046-400-mg-13384