Plaquenil

Formulated to alleviate symptoms of autoimmune conditions, intended to support joint health and relieve inflammation in rheumatoid arthritis and lupus.

Strengths: 200 · 400mg

Medicine details

Therapeutic class

Disease-Modifying Antirheumatic Drug (DMARD)

Pharmacological class

4-Aminoquinoline

Contraindications

retinal damage; hypersensitivity to 4-aminoquinoline derivatives

Precautions and warnings

regular eye exams required for long-term use; may affect blood glucose

Minor side effects

nausea; abdominal discomfort

Moderate side effects

skin rash; headache

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Sanofi

Onset Time

4–12 weeks

Duration

long term

Storage instructions

Store below 25°C in a dry place.

Drug interactions

digoxin; ciclosporin

Age restrictions

Adults.

Serious side effects

retinopathy — requires immediate medical attention; cardiomyopathy — requires immediate medical attention

Patient summary

Formulated to alleviate symptoms of autoimmune conditions, intended to support joint health and relieve inflammation in rheumatoid arthritis and lupus.

Mechanism of action

Hydroxychloroquine acts as an immunomodulator. It reduces the body's inflammatory response by interfering with antigen processing and lysosomal activity within cells, which helps lower the severity of autoimmune flare-ups and provides a protective effect in chronic disease management.

Pregnancy and breastfeeding

Pregnancy: benefits should outweigh risks, discuss with specialist. Breastfeeding: pass into milk, use with caution.

Plaquenil

Formulated to alleviate symptoms of autoimmune conditions, intended to support joint health and relieve inflammation in rheumatoid arthritis and lupus.

Editorial Notes

  • Active ingredient(s): Hydroxychloroquine
  • Listed indication(s): Rheumatoid Arthritis, Systemic Lupus Erythematosus

Usually available as

  • 180 tablets - 200 mg989-200-mg-12391
  • 90 tablets - 400 mg989-400-mg-12397