Tacrolimus Cream
Designed to alleviate atopic dermatitis, utilized to target inflammation and to support to manage compromised skin barrier function.
Strengths: 0.03 · 0.1%
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Medicine details
- Conditions
- Alternative names
Protopic
- Therapeutic class
Calcineurin inhibitor
- Pharmacological class
Immunosuppressant
- Contraindications
hypersensitivity to tacrolimus; netherton syndrome
- Precautions and warnings
minimize sunlight exposure; do not apply to infected skin
- Minor side effects
application site irritation; pruritus
- Moderate side effects
folliculitis; skin infections
- Serious side effects
malignancy — requires immediate medical attention
- Dosage forms
Cream
- Administration route
Cutaneous use
- Prescription status
POM
- Manufacturer
Leo Laboratories
- Onset Time
1 week
- Duration
As directed by physician
- Storage instructions
Store below 25°C.
- Age restrictions
Not for children under 2 years.
Patient summary
Designed to alleviate atopic dermatitis, utilized to target inflammation and to support to manage compromised skin barrier function.
Mechanism of action
Tacrolimus binds to the cytosolic protein FKBP-12, forming a complex that inhibits calcineurin. This inhibits the activation of T-cells and the subsequent release of inflammatory cytokines.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary. Breastfeeding: Monitor usage carefully.
Tacrolimus Cream
Designed to alleviate atopic dermatitis, utilized to target inflammation and to support to manage compromised skin barrier function.
Editorial Notes
- Active ingredient(s): Tacrolimus
- Listed indication(s): Atopic Dermatitis
Available option
- 3 tubes - 0.1 %1197-0-1-pct-14163