Tenofovir
Indicated to mitigate viral replication to support immune system health in chronic infection.
- Category
- HIV Management
- Active ingredient
- Tenofovir
- Supply
- POM
- Route
- Oral use
- Form
- Tablet
- Strengths
- 300mg
Tenofovir details
- Conditions
- HIV Infection · Chronic Hepatitis B
- Alternative names
- Viread
- Registration status
- Registered for use in the UK
- Therapeutic class
- Antiviral agent
- Pharmacological class
- Nucleotide reverse transcriptase inhibitor (NRTI)
- Contraindications
- hypersensitivity to tenofovir
- Minor side effects
- nausea; diarrhoea; headache; fatigue
- Moderate side effects
- flatulence; rash
- Dosage forms
- Tablet
- Administration route
- Oral use
- Prescription status
- Prescription-only medicine (POM)
- Originator
- Gilead Sciences
- Onset Time
- 4–8 weeks
- Duration
- long-term
- Storage instructions
- Store below 30°C in a dry place.
- Drug interactions
- nephrotoxic drugs; didanosine
- Age restrictions
- Follow specialist guidance for paediatric use.
Precautions and warnings
monitor renal function regularly; risk of bone mineral density decrease; screen for hepatitis b before treatment
Serious side effects
renal failure, requires immediate medical attention; lactic acidosis, requires immediate medical attention
Patient summary
indicated to mitigate viral replication to support immune system health in chronic infection.
Mechanism of action
Tenofovir inhibits the activity of the HIV-1 reverse transcriptase and HBV polymerase by causing DNA chain termination after incorporation into DNA.
Pregnancy and breastfeeding
Pregnancy: Benefits should outweigh risks. Breastfeeding: Not recommended for HIV-infected patients.
Registered for use in the UK
- United Kingdom
Tenofovir editorial notes
Tenofovir is a UK-licensed tablet containing Tenofovir Disoproxil, a prescription-only medicine (POM).
Is Tenofovir available in the UK?
Yes, on prescription. Tenofovir Disoproxil is prescription-only in the UK, so it is supplied against a prescription after an assessment by a prescriber. How to check an online pharmacy is legitimate.
Common questions
Can you buy Tenofovir over the counter in the UK? No, it is prescription-only.
What is Tenofovir used for? It is listed for hiv infection and chronic hepatitis b.