Tenofovir
indicated to mitigate viral replication to support immune system health in chronic infection.
Strengths: 300mg
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Medicine details
- Conditions
- Alternative names
Viread
- Therapeutic class
Antiviral agent
- Pharmacological class
Nucleotide reverse transcriptase inhibitor (NRTI)
- Contraindications
hypersensitivity to tenofovir
- Minor side effects
nausea; diarrhoea; headache; fatigue
- Moderate side effects
flatulence; rash
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Gilead Sciences
- Onset Time
4–8 weeks
- Duration
long-term
- Storage instructions
Store below 30°C in a dry place.
- Drug interactions
nephrotoxic drugs; didanosine
- Age restrictions
Follow specialist guidance for paediatric use.
Precautions and warnings
monitor renal function regularly; risk of bone mineral density decrease; screen for hepatitis b before treatment
Serious side effects
renal failure — requires immediate medical attention; lactic acidosis — requires immediate medical attention
Patient summary
indicated to mitigate viral replication to support immune system health in chronic infection.
Mechanism of action
Tenofovir inhibits the activity of the HIV-1 reverse transcriptase and HBV polymerase by causing DNA chain termination after incorporation into DNA.
Pregnancy and breastfeeding
Pregnancy: Benefits should outweigh risks. Breastfeeding: Not recommended for HIV-infected patients.
Tenofovir
indicated to mitigate viral replication to support immune system health in chronic infection.
Editorial Notes
- Active ingredient(s): Tenofovir Disoproxil
- Listed indication(s): HIV Infection, Chronic Hepatitis B
Available option
- 30 tablets - 300 mg1565-300-mg-18267