Epivir Hbv
indicated for chronic hepatitis b to support viral suppression and hepatocyte health.
Strengths: 100mg
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Medicine details
- Conditions
- Alternative names
Zeffix
- Therapeutic class
Antiviral; Nucleoside Reverse Transcriptase Inhibitor
- Pharmacological class
Nucleoside Reverse Transcriptase Inhibitor
- Contraindications
hypersensitivity to lamivudine
- Minor side effects
nausea; headache; malaise; fatigue
- Moderate side effects
elevated liver enzymes; upper respiratory tract infection
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
ViiV Healthcare
- Onset Time
several weeks
- Duration
long-term maintenance
- Storage instructions
Store at ambient temperatures, avoid excessive heat.
- Drug interactions
trimethoprim-sulfamethoxazole; zalcitabine
- Age restrictions
Dosage adjusted based on age and weight for paediatric patients.
Precautions and warnings
monitor for lactic acidosis; regular monitoring of liver function; do not discontinue abruptly
Serious side effects
lactic acidosis — requires immediate medical attention; pancreatitis — requires immediate medical attention; hepatomegaly — requires immediate medical attention
Patient summary
indicated for chronic hepatitis b to support viral suppression and hepatocyte health.
Mechanism of action
Lamivudine is a nucleoside analogue that inhibits the reverse transcriptase of the hepatitis B virus. It is incorporated into viral DNA, causing chain termination and thus halting the replication of the virus.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly needed. Breastfeeding: Advise mothers to discontinue breastfeeding while on therapy.
Epivir Hbv
indicated for chronic hepatitis b to support viral suppression and hepatocyte health.
Editorial Notes
- Active ingredient(s): Lamivudine
- Listed indication(s): Chronic Hepatitis B
Available option
- 60 tablets - 100 mg750-100-mg-1079