Epivir

Developed to manage hiv infection and chronic hepatitis b to support long-term viral suppression.

Strengths: 150mg

HIV Management icon HIV Management Antivirals icon Antivirals Lamivudine icon Lamivudine

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Medicine details

Conditions
Alternative names

Epivir Hbv; Zeffix

Therapeutic class

Nucleoside Reverse Transcriptase Inhibitor (NRTI)

Pharmacological class

Nucleoside analogue

Contraindications

hypersensitivity to lamivudine

Minor side effects

headache; nausea; fatigue

Moderate side effects

elevated liver enzymes; peripheral neuropathy

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

ViiV Healthcare

Onset Time

0.5–2 hours

Duration

12 hours

Storage instructions

Store at room temperature.

Drug interactions

trimethoprim; emtricitabine

Age restrictions

Dosage adjusted for children.

Precautions and warnings

regular blood monitoring recommended; inform your doctor if you experience liver issues

Serious side effects

lactic acidosis — requires immediate medical attention; severe hepatomegaly — requires immediate medical attention

Patient summary

Developed to manage hiv infection and chronic hepatitis b to support long-term viral suppression.

Mechanism of action

Lamivudine is a nucleoside analogue that inhibits human immunodeficiency virus (HIV) reverse transcriptase and hepatitis B virus DNA polymerase. It acts as a chain terminator, preventing successful viral DNA synthesis.

Pregnancy and breastfeeding

Pregnancy: Use as directed by an HIV specialist. Breastfeeding: HIV-positive mothers should generally avoid breastfeeding.

Epivir

Developed to manage hiv infection and chronic hepatitis b to support long-term viral suppression.

Editorial Notes

  • Active ingredient(s): Lamivudine
  • Listed indication(s): HIV Infection, Chronic Hepatitis B

Available option

  • 60 tablets - 150 mg127-150-mg-1073