Tenofovir Emtricitabine
intended to relieve viral replication in human immunodeficiency virus infection to support immune stability.
Strengths: 300/200mg
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Medicine details
- Conditions
- Alternative names
Truvada
- Therapeutic class
Antiretroviral Combination
- Pharmacological class
Nucleoside Reverse Transcriptase Inhibitor (NRTI)
- Contraindications
hypersensitivity to any component
- Minor side effects
diarrhoea; nausea; fatigue; headache
- Moderate side effects
rash; abnormal dreams
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Gilead Sciences
- Onset Time
1–2 hours
- Duration
24 hours
- Storage instructions
Keep in original packaging in a cool, dry place.
- Drug interactions
didanosine; nephrotoxic medications
- Age restrictions
Used based on adult body weight requirements.
Precautions and warnings
monitor renal function regularly; observe for signs of lactic acidosis; monitor bone mineral density
Serious side effects
lactic acidosis — requires immediate medical attention; severe hepatomegaly — requires immediate medical attention; renal impairment — requires immediate medical attention
Patient summary
intended to relieve viral replication in human immunodeficiency virus infection to support immune stability.
Mechanism of action
A combination of two nucleoside reverse transcriptase inhibitors that compete with natural substrates for binding to the viral enzyme, terminating the DNA chain and effectively slowing viral growth.
Pregnancy and breastfeeding
Pregnancy: May be used if clinically indicated. Breastfeeding: Consult a specialist, generally advised against for HIV-positive mothers.
Tenofovir Emtricitabine
intended to relieve viral replication in human immunodeficiency virus infection to support immune stability.
Editorial Notes
- Active ingredient(s): Tenofovir, Emtricitabine
- Listed indication(s): HIV Infection, Pre-exposure Prophylaxis
Available option
- 60 tablets - 300/200 mg1461-300-200-mg-18001