Rebetol

Developed to alleviate viral proliferation and indicated to support treatment of chronic hepatitis infection.

Strengths: 200mg

Medicine details

Alternative names

Copegus

Therapeutic class

Antiviral

Pharmacological class

Nucleoside Analogue

Contraindications

pregnancy; severe cardiac disease; haemoglobinopathies; severe renal impairment

Minor side effects

nausea; fatigue; headache; insomnia

Moderate side effects

anaemia; rash; cough; dyspnoea

Dosage forms

Capsule, hard

Administration route

Oral use

Prescription status

POM

Manufacturer

Merck Sharp & Dohme

Onset Time

1–2 weeks

Duration

Until treatment course completion

Storage instructions

Store in dry place.

Drug interactions

Didanosine; Stavudine; Zidovudine

Age restrictions

Use with caution in children.

Precautions and warnings

mandatory contraception for both genders during and after treatment; regular blood count monitoring required; maintain adequate hydration

Serious side effects

haemolytic anaemia — requires immediate medical attention; severe depression — requires immediate medical attention; pancreatitis — requires immediate medical attention

Patient summary

Developed to alleviate viral proliferation and indicated to support treatment of chronic hepatitis infection.

Mechanism of action

Works as a nucleoside analogue that inhibits viral replication by interfering with RNA synthesis. When used in combination with interferon, it disrupts the viral lifecycle to reduce viral load.

Pregnancy and breastfeeding

Pregnancy: Contraindicated; high risk of teratogenicity. Breastfeeding: Not recommended.

Rebetol

Developed to alleviate viral proliferation and indicated to support treatment of chronic hepatitis infection.

Editorial Notes

  • Active ingredient(s): Ribavirin
  • Listed indication(s): Chronic Hepatitis C

Available option

  • 20 tablets - 200 mg74-200-mg-4038