Daklinza

Developed to alleviate chronic hepatitis C infection, indicated to target the virus and support sustained virologic response.

Strengths: 60mg

Medicine details

Therapeutic class

Direct-acting antiviral

Pharmacological class

NS5A inhibitor

Contraindications

hypersensitivity to daclatasvir; concurrent use of strong inducers of CYP3A4

Precautions and warnings

monitor liver enzymes during treatment

Minor side effects

headache; fatigue; nausea

Moderate side effects

anaemia; insomnia; diarrhoea

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Bristol-Myers Squibb

Onset Time

Continuous therapy

Duration

12–24 weeks

Storage instructions

Store in a cool dry place.

Drug interactions

amiodarone; carbamazepine; phenytoin

Age restrictions

Adults

Serious side effects

bradycardia — requires immediate medical attention; liver failure — requires immediate medical attention

Patient summary

Developed to alleviate chronic hepatitis C infection, indicated to target the virus and support sustained virologic response.

Mechanism of action

Daclatasvir inhibits the NS5A protein, which is essential for both viral RNA replication and virion assembly, thus preventing the virus from multiplying.

Pregnancy and breastfeeding

Pregnancy: Should not be used during pregnancy unless necessary. Breastfeeding: Avoid during treatment.

Daklinza

Developed to alleviate chronic hepatitis C infection, indicated to target the virus and support sustained virologic response.

Editorial Notes

  • Active ingredient(s): Daclatasvir
  • Listed indication(s): Chronic Hepatitis C

Available option

  • 28 tablets - 60 mg863-60-mg-6366