Velpanat

Utilized to address chronic hepatitis c and indicated to support viral clearance.

Strengths: 400/100mg

Medicine details

Alternative names

Epclusa

Therapeutic class

Antiviral

Pharmacological class

HCV NS5B inhibitor; HCV NS5A inhibitor

Contraindications

hypersensitivity to active substances

Precautions and warnings

monitor hepatic function

Minor side effects

headache; fatigue; nausea

Moderate side effects

insomnia; rash

Serious side effects

bradycardia — requires immediate medical attention

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Natco Pharma

Onset Time

not applicable

Duration

24 hours

Storage instructions

Store below 30°C.

Drug interactions

Amiodarone; Proton pump inhibitors; St. John's Wort

Age restrictions

For adult use.

Patient summary

Utilized to address chronic hepatitis c and indicated to support viral clearance.

Mechanism of action

Velpanat combines a nucleotide polymerase inhibitor (sofosbuvir) and a replication complex inhibitor (velpatasvir) to block hepatitis C virus replication, effectively targeting the viral life cycle.

Pregnancy and breastfeeding

Pregnancy: Not recommended unless necessary provided by specialist. Breastfeeding: Consult specialist.

Velpanat

Utilized to address chronic hepatitis c and indicated to support viral clearance.

Editorial Notes

  • Active ingredient(s): Sofosbuvir, Velpatasvir
  • Listed indication(s): Chronic Hepatitis C

Available option

  • 28 tablets - 400/100 mg1454-400-100-mg-17500