Natdac
A direct-acting antiviral for chronic hepatitis C, taken alongside a second antiviral for a course of several weeks.
- Category
- Antivirals
- Active ingredient
- Daclatasvir
- Supply
- POM
- Route
- Oral use
- Form
- Tablet
- Strengths
- 60mg
Natdac details
- Condition
- Chronic Hepatitis C
- Alternative names
- Daklinza
- Registration status
- Not registered in the UK
- Therapeutic class
- Direct-Acting Antiviral
- Pharmacological class
- NS5A Inhibitor
- Contraindications
- hypersensitivity to active components
- Minor side effects
- fatigue; headache; nausea
- Moderate side effects
- insomnia; dizziness; diarrhoea
- Dosage forms
- Tablet
- Administration route
- Oral use
- Prescription status
- Prescription-only medicine (POM)
- Manufacturer
- Natco Pharma
- Onset Time
- 1–2 weeks
- Duration
- 12–24 weeks
- Storage instructions
- Store in original packaging.
- Drug interactions
- amiodarone; rifampicin; st. john's wort
- Age restrictions
- For adults.
- Pregnancy and breastfeeding
- Pregnancy: Not recommended. Breastfeeding: Not recommended.
Precautions and warnings
monitor for hepatitis b reactivation; frequent monitoring of liver function; no alcohol consumption
Serious side effects
hepatitis b reactivation, requires immediate medical attention; severe bradycardia, requires immediate medical attention
Patient summary
A direct-acting antiviral for chronic hepatitis C, taken alongside a second antiviral for a course of several weeks.
Mechanism of action
Daclatasvir inhibits the hepatitis C NS5A protein, which the virus needs both to copy its RNA and to assemble new particles. It is taken with a second direct-acting antiviral, usually sofosbuvir, never on its own.
Not registered in the UK
- United Kingdom
Natdac editorial notes
Natdac is Natco Pharma’s brand of daclatasvir 60mg, and it is not registered in the UK.
Is Natdac available in the UK?
Natdac is not a UK-licensed product. Daclatasvir itself was approved in the UK as Daklinza, though the manufacturer withdrew it once combination tablets took over. The licensed route to hepatitis C treatment now runs through a specialist hepatology service rather than a retail pharmacy. How buying medicines from abroad works.
Common questions
Is Natdac the same as Daklinza? Both are daclatasvir 60mg. Daklinza was the originator brand from Bristol-Myers Squibb; Natdac is Natco Pharma’s version.
Is daclatasvir taken on its own? No. It is an NS5A inhibitor and is always combined with a second direct-acting antiviral, most often sofosbuvir. See daclatasvir.
Where to Check Availability
OK Healthy doesn't sell or supply medicines. These are independent external pharmacies, so check current availability and prices on their own sites.
These links open external pharmacy websites, not OK Healthy, and some are affiliate links, and we may earn a commission at no extra cost to you.How to check an online pharmacy is legitimate