Sporanox
This medication is formulated to help manage severe fungal infections and intended to relieve symptoms associated with systemic candidiasis or aspergillosis.
Strengths: 100mg
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Medicine details
- Therapeutic class
Antifungal
- Pharmacological class
Triazole
- Precautions and warnings
monitor hepatic function; observe for signs of heart failure
- Minor side effects
nausea; abdominal discomfort; headache
- Moderate side effects
oedema; hypertension; rash
- Dosage forms
Capsule, hard
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Janssen-Cilag
- Onset Time
1–2 weeks
- Duration
2–6 months
- Storage instructions
Store at room temperature below 25°C.
- Drug interactions
Statins; Midazolam; Digoxin; Warfarin
- Age restrictions
Use with caution in elderly patients.
- Pregnancy and breastfeeding
Pregnancy: avoid unless strictly necessary. Breastfeeding: not advised.
Contraindications
hypersensitivity to triazoles; heart failure; ventricular dysfunction; concurrent use of certain cardiac medications
Serious side effects
congestive heart failure — requires immediate medical attention; hepatotoxicity — requires immediate medical attention
Patient summary
This medication is formulated to help manage severe fungal infections and intended to relieve symptoms associated with systemic candidiasis or aspergillosis.
Mechanism of action
Itraconazole is a potent inhibitor of fungal cytochrome P450-dependent enzymes. This inhibits the synthesis of ergosterol, which is essential for fungal cell membrane integrity, resulting in the inhibition of fungal cell growth.
Sporanox
This medication is formulated to help manage severe fungal infections and intended to relieve symptoms associated with systemic candidiasis or aspergillosis.
Editorial Notes
- Active ingredient(s): Itraconazole
- Listed indication(s): Candidiasis, Histoplasmosis, Aspergillosis, Tinea
Available option
- 20 tablets - 100 mg95-100-mg-1464