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Medicine details

Conditions: Type 2 Diabetes Mellitus
Alternative names: Glucophage
Therapeutic class: Biguanide Antidiabetic
Pharmacological class: Biguanide
Known off-label uses: polycystic ovary syndrome
Contraindications: renal impairment; diabetic ketoacidosis; severe hepatic impairment
Minor side effects: nausea; diarrhoea; abdominal pain; loss of appetite
Moderate side effects: metallic taste; vitamin B12 deficiency
Serious side effects: lactic acidosis — requires immediate medical attention
Dosage forms: Tablet
Administration route: Oral use
Prescription status: POM
Manufacturer: USV Private Limited
Onset Time: 1–2 weeks
Duration: indefinite
Storage instructions: Store at room temperature in a dry place.
Drug interactions: alcohol; iodinated contrast agents; corticosteroids
Age restrictions: Suitable for adults; specific paediatric approval varies by formulation.

Precautions and warnings

discontinue before surgery; regular blood glucose monitoring necessary; risk of vitamin B12 deficiency

Patient summary

intended to target high blood sugar levels and to support metabolic control in diabetes.

Mechanism of action

Reduces hepatic glucose production and improves insulin sensitivity, enhancing peripheral glucose uptake without causing hypoglycaemia.

Pregnancy and breastfeeding

Pregnancy: Insulin is preferred for glucose control during pregnancy. Breastfeeding: Generally considered safe.

intended to target high blood sugar levels and to support metabolic control in diabetes.