Glucophage Xr
utilized to manage type 2 diabetes mellitus and indicated to support glucose control effectively for improved endocrine function.
Strengths: 1000mg
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Medicine details
- Conditions
- Alternative names
Glucophage SR
- Therapeutic class
Biguanide Antidiabetic
- Pharmacological class
Biguanide
- Contraindications
diabetic ketoacidosis; severe renal impairment; hypersensitivity to metformin
- Minor side effects
nausea; vomiting; diarrhoea; abdominal pain
- Moderate side effects
metallic taste; decreased vitamin B12 absorption
- Serious side effects
lactic acidosis — requires immediate medical attention
- Dosage forms
Prolonged-release tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Merck
- Onset Time
4–8 weeks
- Duration
24 hours
- Storage instructions
Store in a cool, dry place.
- Drug interactions
alcohol; iodinated contrast media
- Age restrictions
Use in children over 10 years only if prescribed.
Precautions and warnings
monitor blood glucose regularly; risk of lactic acidosis if kidney function is compromised; discontinue before major surgery
Patient summary
utilized to manage type 2 diabetes mellitus and indicated to support glucose control effectively for improved endocrine function.
Mechanism of action
Metformin works by reducing glucose production by the liver, decreasing intestinal glucose absorption, and increasing insulin sensitivity to improve peripheral glucose uptake and utilization.
Pregnancy and breastfeeding
Pregnancy: standard treatment for gestational diabetes, usually discussed with a specialist. Breastfeeding: generally considered compatible but requires monitoring.
Glucophage Xr
utilized to manage type 2 diabetes mellitus and indicated to support glucose control effectively for improved endocrine function.
Editorial Notes
- Active ingredient(s): Metformin
- Listed indication(s): Type 2 Diabetes Mellitus
Available option
- 60 tablets - 1000 mg691-1000-mg-15516