Glucophage
Formulated to target type 2 diabetes mellitus to alleviate hyperglycemia through improved insulin sensitivity.
Strengths: 500 · 850 · 1000mg
Where to Check Availability
Medicine details
- Conditions
- Alternative names
Metabet; Glucophage SR
- Therapeutic class
Biguanide Antidiabetic
- Pharmacological class
Biguanide
- Known off-label uses
polycystic ovary syndrome
- Contraindications
severe renal impairment; diabetic ketoacidosis; hypersensitivity
- Minor side effects
nausea; vomiting; diarrhoea
- Moderate side effects
abdominal pain; loss of appetite
- Serious side effects
lactic acidosis — requires immediate medical attention
- Dosage forms
Film-coated tablet; Prolonged-release tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Merck KGaA
- Onset Time
2–3 hours
- Duration
6–12 hours
- Storage instructions
Store at room temperature in the original packaging.
- Drug interactions
Alcohol; Iodinated contrast agents
- Age restrictions
Consult specialist for use in children.
Precautions and warnings
monitor kidney function; withdraw before contrast imaging; risk of vitamin b12 deficiency
Patient summary
Formulated to target type 2 diabetes mellitus to alleviate hyperglycemia through improved insulin sensitivity.
Mechanism of action
This treatment works by reducing glucose production in the liver, decreasing intestinal glucose absorption, and enhancing the body's sensitivity to insulin. It effectively helps maintain blood sugar levels in the target range.
Pregnancy and breastfeeding
Pregnancy: Insulin is usually preferred for blood glucose control during pregnancy. Breastfeeding: Small amounts may be present in milk; consult a physician.
Glucophage
Formulated to target type 2 diabetes mellitus to alleviate hyperglycemia through improved insulin sensitivity.
Editorial Notes
- Active ingredient(s): Metformin
- Listed indication(s): Type 2 Diabetes Mellitus
Usually available as
- 360 tablets - 850 mg261-850-mg-3065
- 180 tablets - 1000 mg261-1000-mg-3070