Actoplus Met
indicated to support blood sugar regulation in patients with metabolic conditions.
Strengths: 500/15mg
Where to Check Availability
Medicine details
- Conditions
- Therapeutic class
Biguanide; Thiazolidinedione
- Pharmacological class
Biguanide; Thiazolidinedione
- Contraindications
diabetic ketoacidosis; severe renal impairment; heart failure
- Minor side effects
nausea; diarrhoea
- Moderate side effects
peripheral oedema; weight gain
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Takeda Pharmaceutical
- Onset Time
1–2 weeks
- Duration
24 hours
- Storage instructions
Store below 25°C.
- Drug interactions
alcohol; iodinated contrast agents
- Age restrictions
Adult use only.
- Pregnancy and breastfeeding
Pregnancy: Seek specialist advice. Breastfeeding: Not recommended.
Precautions and warnings
monitor liver function; regular glucose testing; observe for signs of bladder cancer
Serious side effects
lactic acidosis — requires immediate medical attention; heart failure — requires immediate medical attention
Patient summary
indicated to support blood sugar regulation in patients with metabolic conditions.
Mechanism of action
Metformin decreases glucose production in the liver and improves insulin sensitivity, while pioglitazone activates PPAR-gamma to increase cellular glucose uptake.
Actoplus Met
indicated to support blood sugar regulation in patients with metabolic conditions.
Editorial Notes
- Active ingredient(s): Metformin, Pioglitazone
- Listed indication(s): Type 2 Diabetes Mellitus
Available option
- 90 tablets - 500/15 mg1047-500-15-mg-13195