Gemfibrozil Tablets
Indicated to target high triglycerides, utilized to manage lipid profiles.
Strengths: 300mg
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Medicine details
- Conditions
- Alternative names
Lopid
- Therapeutic class
Fibrate
- Pharmacological class
PPAR Alpha Agonist
- Minor side effects
dyspepsia; abdominal pain; diarrhoea
- Moderate side effects
dizziness; fatigue; skin rash
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Patient summary
Indicated to target high triglycerides, utilized to manage lipid profiles.
- Prescription status
POM
- Manufacturer
Pfizer
- Onset Time
3–5 days
- Duration
12–24 hours
- Storage instructions
Store below 25°C.
- Drug interactions
statins; warfarin; repaglinide
- Age restrictions
Adults only
- Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Avoid during treatment.
Contraindications
hypersensitivity to gemfibrozil; hepatic impairment; severe renal impairment; pre-existing gallbladder disease
Precautions and warnings
regular blood monitoring required; report unexplained muscle pain; monitor liver function
Serious side effects
rhabdomyolysis — requires immediate medical attention; cholelithiasis — requires immediate medical attention
Mechanism of action
Gemfibrozil is a fibrate that acts as a PPAR-alpha agonist. It increases lipolysis and decreases hepatic production of triglyceride-rich lipoproteins, effectively lowering serum triglyceride levels and increasing HDL cholesterol.
Gemfibrozil Tablets
Indicated to target high triglycerides, utilized to manage lipid profiles.
Editorial Notes
- Active ingredient(s): Gemfibrozil
- Listed indication(s): Hypertriglyceridaemia
Available option
- 60 tablets - 300 mg1390-300-mg-16667