Ezetimibe Tablets
designed to mitigate high cholesterol levels indicated to support cardiovascular function.
Strengths: 10mg
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Medicine details
- Conditions
- Alternative names
Ezetrol
- Therapeutic class
Cholesterol Absorption Inhibitor
- Pharmacological class
Cholesterol Absorption Inhibitor
- Contraindications
hypersensitivity; active liver disease
- Precautions and warnings
monitor liver function enzymes when combined with statins
- Minor side effects
fatigue; abdominal pain; diarrhoea
- Moderate side effects
myalgia; elevated liver enzymes
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Merck Sharp & Dohme
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store below 30°C in the original container.
- Drug interactions
ciclosporin; warfarin
- Age restrictions
Dosage titration monitored by physician in adolescents.
- Pregnancy and breastfeeding
Use not recommended without specialist advice.
Serious side effects
rhabdomyolysis — requires immediate medical attention; hepatitis — requires immediate medical attention
Patient summary
designed to mitigate high cholesterol levels indicated to support cardiovascular function.
Mechanism of action
Ezetimibe inhibits cholesterol absorption at the brush border of the small intestine, blocking the Niemann-Pick C1-like 1 (NPC1L1) transporter protein and reducing deliver of cholesterol to the liver.
Ezetimibe Tablets
designed to mitigate high cholesterol levels indicated to support cardiovascular function.
Editorial Notes
- Active ingredient(s): Ezetimibe
- Listed indication(s): Hypercholesterolaemia
Available option
- 90 tablets - 10 mg1381-10-mg-16577