Efudex
utilized to target actinic keratosis and intended to support the reduction of cancerous skin cell proliferation.
Strengths: 1 · 5%
Where to Check Availability
Medicine details
- Conditions
- Alternative names
Efudix
- Therapeutic class
Antineoplastic agent
- Pharmacological class
Antimetabolite
- Known off-label uses
viral warts
- Contraindications
hypersensitivity to fluorouracil; pregnancy
- Minor side effects
burning; stinging; erythema; pruritus
- Moderate side effects
erosions; ulceration; dermatitis
- Serious side effects
severe inflammatory reaction — requires immediate medical attention
- Dosage forms
Cream
- Administration route
Cutaneous use
- Prescription status
POM
- Manufacturer
Viatris
- Onset Time
2–4 weeks
- Duration
3–6 weeks
- Storage instructions
Store between 15°C and 25°C.
Precautions and warnings
avoid exposure to sunlight; wash hands thoroughly after application; do not apply to mucosal surfaces
Patient summary
utilized to target actinic keratosis and intended to support the reduction of cancerous skin cell proliferation.
Mechanism of action
Fluorouracil is an antimetabolite that inhibits thymidylate synthase, thereby interfering with DNA synthesis in rapidly dividing cells, which leads to the selective destruction of actinic keratosis and neoplastic skin lesions.
Pregnancy and breastfeeding
Pregnancy: Contraindicated. Breastfeeding: Not recommended due to potential systemic absorption.
Efudex
utilized to target actinic keratosis and intended to support the reduction of cancerous skin cell proliferation.
Editorial Notes
- Active ingredient(s): Fluorouracil
- Listed indication(s): Actinic Keratosis, Basal Cell Carcinoma
Available option
- 5 tubes - 5 %1035-5-pct-13003