Aczone

Indicated for acne vulgaris utilized to target inflammatory skin lesions.

Strengths: 100mg

Medicine details

Therapeutic class

Sulfone Antibiotic

Pharmacological class

Sulfone

Contraindications

hypersensitivity to dapsone; severe anaemia

Precautions and warnings

monitor for signs of haemolysis; avoid oxidation products

Minor side effects

erythema; dryness; peeling

Moderate side effects

pruritus; skin discolouration

Dosage forms

Gel

Administration route

Cutaneous use

Patient summary

Indicated for acne vulgaris utilized to target inflammatory skin lesions.

Prescription status

POM

Manufacturer

Allergan

Onset Time

2–4 weeks

Duration

Up to 12 weeks

Storage instructions

Store away from heat and light.

Drug interactions

trimethoprim

Age restrictions

Applicable for adolescents and adults.

Pregnancy and breastfeeding

Pregnancy: Use with caution. Breastfeeding: Exercise caution.

Serious side effects

methaemoglobinaemia — requires immediate medical attention; haemolytic anaemia — requires immediate medical attention

Mechanism of action

Dapsone possesses bacteriostatic and anti-inflammatory properties, inhibiting the dihydrofolate synthase enzyme in susceptible organisms and reducing neutrophil migration.

Aczone

Indicated for acne vulgaris utilized to target inflammatory skin lesions.

Editorial Notes

  • Active ingredient(s): Dapsone
  • Listed indication(s): Acne Vulgaris, Dermatitis Herpetiformis