Adapalen

Indicated to address acne vulgaris to alleviate skin inflammation.

Strengths: 15g

Medicine details

Conditions
Alternative names

Differin

Therapeutic class

Retinoid

Pharmacological class

Retinoid

Contraindications

hypersensitivity to adapalene; severe eczema

Minor side effects

erythema; skin dryness; skin peeling

Moderate side effects

pruritus; sunburn

Serious side effects

dermatitis — requires immediate medical attention

Dosage forms

Gel

Administration route

Cutaneous use

Patient summary

Indicated to address acne vulgaris to alleviate skin inflammation.

Prescription status

POM

Manufacturer

Galderma

Onset Time

8–12 weeks

Duration

Ongoing use

Storage instructions

Store below 25°C. Do not freeze.

Age restrictions

Use with caution in adolescents.

Precautions and warnings

avoid contact with eyes and mucous membranes; use sun protection as skin may become sensitive; limit concurrent use of other drying skin treatments

Mechanism of action

Adapalene is a retinoid-like compound that modulates keratinization and cellular differentiation. It binds to specific retinoic acid nuclear receptors to exert anti-inflammatory effects and normalize skin cell turnover, reducing comedone formation.

Pregnancy and breastfeeding

Pregnancy: Avoid use. Breastfeeding: Use with caution as safety is not fully established.

Adapalen

Indicated to address acne vulgaris to alleviate skin inflammation.

Editorial Notes

  • Active ingredient(s): Adapalene
  • Listed indication(s): Acne Vulgaris

Available option

  • 5 tubes - 15 g1225-15-g-14596