Valtrex

Indicated to manage herpes zoster and herpes simplex virus infection to alleviate painful outbreaks and speed recovery.

Strengths: 500 · 1000mg

Medicine details

Alternative names

Valaciclovir

Therapeutic class

Antiviral Agent

Pharmacological class

Nucleoside analogue

Contraindications

hypersensitivity to valaciclovir

Precautions and warnings

maintain adequate fluid intake; use with caution in elderly patients

Minor side effects

headache; nausea

Moderate side effects

dizziness; abdominal pain

Dosage forms

Film-coated tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

GSK

Onset Time

1–2 hours

Duration

8–12 hours

Storage instructions

Store at room temperature.

Drug interactions

nephrotoxic agents

Age restrictions

Dose adjustment required for patients with renal impairment and the elderly.

Serious side effects

renal impairment — requires immediate medical attention; neurological symptoms — requires immediate medical attention

Patient summary

Indicated to manage herpes zoster and herpes simplex virus infection to alleviate painful outbreaks and speed recovery.

Mechanism of action

Valaciclovir is a prodrug of acyclovir. It is converted rapidly to acyclovir in the body, which selectively inhibits viral DNA polymerase, thereby interrupting DNA synthesis in herpes viruses.

Pregnancy and breastfeeding

Pregnancy: Use only if clearly needed. Breastfeeding: Use with caution; monitor the infant.

Valtrex

Indicated to manage herpes zoster and herpes simplex virus infection to alleviate painful outbreaks and speed recovery.

Editorial Notes

  • Active ingredient(s): Valacyclovir
  • Listed indication(s): Herpes Zoster, Herpes Simplex

Usually available as

  • 36 tablets - 500 mg128-500-mg-5940
  • 24 tablets - 1000 mg128-1000-mg-5933