Zovirax
Formulated to target herpes simplex virus infection to alleviate painful symptoms and support healing.
Strengths: 200 · 400 · 800mg
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Medicine details
- Conditions
- Therapeutic class
Antiviral Agent
- Pharmacological class
Nucleoside analogue
- Contraindications
hypersensitivity to acyclovir
- Precautions and warnings
maintain adequate hydration; use with caution in patients with renal impairment
- Minor side effects
nausea; headache
- Moderate side effects
fatigue; skin rash
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
GSK
- Onset Time
1–2 hours
- Duration
4–5 hours
- Storage instructions
Keep cool and dry.
- Drug interactions
probenecid
- Age restrictions
Suitable for all ages with appropriate dosing.
Serious side effects
neurological reactions — requires immediate medical attention; reversible renal impairment — requires immediate medical attention
Patient summary
Formulated to target herpes simplex virus infection to alleviate painful symptoms and support healing.
Mechanism of action
Acyclovir is a nucleoside analogue that is phosphorylated by the viral thymidine kinase. The resulting triphosphate inhibits viral DNA polymerase, preventing viral genome replication in herpes-infected cells.
Pregnancy and breastfeeding
Pregnancy: Use only if potential benefit outweighs risk. Breastfeeding: Excreted in breast milk; use with caution.
Zovirax
Formulated to target herpes simplex virus infection to alleviate painful symptoms and support healing.
Editorial Notes
- Active ingredient(s): Acyclovir
- Listed indication(s): Herpes Simplex, Varicella Zoster Infection
Usually available as
- 360 tablets - 200 mg129-200-mg-5369
- 180 tablets - 400 mg129-400-mg-5376
- 60 tablets - 800 mg129-800-mg-11391