Tretiva
Designed to target severe acne, this retinoid is indicated to support the reduction of cysts and is utilized to alleviate persistent skin outbreaks.
Strengths: 5 · 10 · 20 · 30mg
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Medicine details
- Conditions
- Alternative names
Roaccutane
- Therapeutic class
Retinoid
- Pharmacological class
Retinoid
- Minor side effects
dry skin; dry lips; dry eyes; nosebleeds
- Moderate side effects
myalgia; elevated liver enzymes; hypertriglyceridaemia
- Dosage forms
Capsule, soft
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Intas Pharmaceuticals
- Onset Time
2–4 weeks
- Duration
4–6 months
- Storage instructions
Store below 25°C in original packaging.
- Drug interactions
vitamin a supplements; tetracyclines; st. john's wort
- Age restrictions
Use with caution in adolescents.
Contraindications
pregnancy; breastfeeding; severe hepatic impairment; hypervitaminosis a; hyperlipidaemia
Precautions and warnings
must avoid pregnancy; avoid blood donation during treatment; avoid excessive sun exposure
Serious side effects
teratogenicity — requires immediate medical attention; depression — requires immediate medical attention; pancreatitis — requires immediate medical attention
Patient summary
Designed to target severe acne, this retinoid is indicated to support the reduction of cysts and is utilized to alleviate persistent skin outbreaks.
Mechanism of action
Isotretinoin reduces sebaceous gland activity and size, inhibits keratinization, and modulates inflammation, significantly decreasing the production of sebum that contributes to acne.
Pregnancy and breastfeeding
Pregnancy: Strictly contraindicated; high risk of severe birth defects. Breastfeeding: Contraindicated.
Tretiva
Designed to target severe acne, this retinoid is indicated to support the reduction of cysts and is utilized to alleviate persistent skin outbreaks.
Editorial Notes
- Active ingredient(s): Isotretinoin
- Listed indication(s): Severe Acne, Nodulocystic Acne
Usually available as
- 90 tablets - 5 mg1088-5-mg-15307
- 90 tablets - 10 mg1088-10-mg-15292
- 60 tablets - 20 mg1088-20-mg-15296