Trazodone Tablets
Developed to target depressive disorders, utilized to support patients to alleviate symptoms of low mood and anxiety through regulated serotonin modulation.
Strengths: 25 · 50 · 100mg
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Medicine details
- Conditions
- Alternative names
Molipaxin
- Therapeutic class
antidepressant
- Pharmacological class
serotonin antagonist and reuptake inhibitor (SARI)
- Known off-label uses
insomnia
- Contraindications
acute recovery phase of myocardial infarction; hypersensitivity
- Precautions and warnings
may cause drowsiness
- Minor side effects
drowsiness; dry mouth
- Moderate side effects
dizziness; headache; nausea
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Sanofi
- Onset Time
1–2 weeks
- Duration
Half-life ~7 hours
- Storage instructions
Store below 25°C.
- Drug interactions
alcohol; fluoxetine; monoamine oxidase inhibitors
- Age restrictions
Not for children and adolescents under 18 years.
- Pregnancy and breastfeeding
Pregnancy: use with caution. Breastfeeding: use with caution.
Serious side effects
priapism — requires immediate medical attention; serotonin syndrome — requires immediate medical attention
Patient summary
Developed to target depressive disorders, utilized to support patients to alleviate symptoms of low mood and anxiety through regulated serotonin modulation.
Mechanism of action
Trazodone is a serotonin antagonist and reuptake inhibitor. It inhibits the reuptake of serotonin presynaptically while also antagonising 5-HT2A receptors. This dual-action approach helps to improve mood and sleep patterns.
Trazodone Tablets
Developed to target depressive disorders, utilized to support patients to alleviate symptoms of low mood and anxiety through regulated serotonin modulation.
Editorial Notes
- Active ingredient(s): Trazodone
- Listed indication(s): Major Depressive Disorder, Anxiety
Usually available as
- 360 tablets - 25 mg1164-25-mg-13758
- 360 tablets - 50 mg1164-50-mg-13764
- 120 tablets - 100 mg1164-100-mg-13768