Sinequan

This medication is indicated to address depression and anxiety-related symptoms and intended to support mood stabilization in patients.

Strengths: 10 · 25 · 75mg

Medicine details

Therapeutic class

Tricyclic Antidepressant

Pharmacological class

Tricyclic Antidepressant (TCA)

Known off-label uses

insomnia

Contraindications

urinary retention; narrow-angle glaucoma; concurrent use of MAO inhibitors

Precautions and warnings

may cause drowsiness; caution in prostatic hypertrophy

Minor side effects

dry mouth; blurred vision; constipation; drowsiness

Moderate side effects

tachycardia; orthostatic hypotension

Dosage forms

Capsule, hard

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

2–3 weeks

Duration

long-term

Storage instructions

Store at room temperature in a dry place.

Drug interactions

Alcohol; Antihistamines; MAO inhibitors

Age restrictions

Use with caution in elderly patients.

Pregnancy and breastfeeding

Pregnancy: consult a doctor. Breastfeeding: not recommended.

Serious side effects

suicidal ideation — requires immediate medical attention; cardiac arrhythmia — requires immediate medical attention

Patient summary

This medication is indicated to address depression and anxiety-related symptoms and intended to support mood stabilization in patients.

Mechanism of action

Doxepin acts by inhibiting the reuptake of both serotonin and norepinephrine in the central nervous system synapses, thereby increasing their concentration and improving mood.

Sinequan

This medication is indicated to address depression and anxiety-related symptoms and intended to support mood stabilization in patients.

Editorial Notes

  • Active ingredient(s): Doxepin
  • Listed indication(s): Major Depressive Disorder, Anxiety

Usually available as

  • 360 tablets - 10 mg98-10-mg-4193
  • 90 tablets - 25 mg98-25-mg-4199
  • 90 tablets - 75 mg98-75-mg-4207