Mirtazapine Tablets
utilized to manage major depressive disorder to alleviate persistent low mood and emotional instability.
Strengths: 7.5 · 15 · 30mg
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Medicine details
- Conditions
- Alternative names
Zispin; Zispin SolTab
- Therapeutic class
Tetracyclic Antidepressant
- Pharmacological class
Tetracyclic Antidepressant
- Known off-label uses
generalized anxiety disorder
- Contraindications
hypersensitivity to mirtazapine; concurrent use of monoamine oxidase inhibitors
- Minor side effects
drowsiness; sedation; dry mouth; increased appetite; weight gain
- Moderate side effects
dizziness; lethargy; oedema; arthralgia
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Organon Pharma
- Onset Time
1–2 weeks
- Duration
indefinite
- Storage instructions
Store in original packaging below 30°C.
- Drug interactions
alcohol; monoamine oxidase inhibitors; benzodiazepines
- Age restrictions
Not recommended for children and adolescents under 18 years.
Precautions and warnings
may impair ability to drive or operate machinery; monitor for changes in mood or behaviour
Serious side effects
serotonin syndrome — requires immediate medical attention; severe neutropenia — requires immediate medical attention; convulsions — requires immediate medical attention
Patient summary
utilized to manage major depressive disorder to alleviate persistent low mood and emotional instability.
Mechanism of action
Mirtazapine works by increasing the release of norepinephrine and serotonin in the central nervous system. It acts as an antagonist at presynaptic alpha-2 adrenergic receptors, which enhances neurotransmitter signalling, helping to regulate mood and restore emotional balance in patients with depression.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary after medical consultation. Breastfeeding: Discuss with your doctor as transfer into breast milk is possible.
Mirtazapine Tablets
utilized to manage major depressive disorder to alleviate persistent low mood and emotional instability.
Editorial Notes
- Active ingredient(s): Mirtazapine
- Listed indication(s): Major Depressive Disorder
Usually available as
- 180 tablets - 7.5 mg1199-7-5-mg-14187
- 180 tablets - 15 mg1199-15-mg-14192
- 90 tablets - 30 mg1199-30-mg-14195