Amitriptyline Tablets
Designed to mitigate major depressive disorder and neuropathic pain, indicated to support mood regulation and provide effective relief for chronic nerve discomfort.
Strengths: 10 · 25 · 50 · 75mg
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Medicine details
- Alternative names
Elavil; Tryptizol; Endep
- Therapeutic class
Tricyclic Antidepressant
- Pharmacological class
Tricyclic Antidepressant (TCA)
- Known off-label uses
migraine prophylaxis
- Contraindications
recent myocardial infarction; heart block
- Precautions and warnings
may impair ability to drive
- Minor side effects
dry mouth; drowsiness
- Moderate side effects
blurred vision; constipation; urinary retention
- Serious side effects
cardiac arrhythmia — requires immediate medical attention
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Onset Time
2–4 weeks
- Duration
24 hours
- Storage instructions
Store at room temperature, protected from moisture.
- Drug interactions
Alcohol; MAOIs
- Age restrictions
Use with caution in elderly patients.
- Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Use with caution as excreted in milk.
Patient summary
Designed to mitigate major depressive disorder and neuropathic pain, indicated to support mood regulation and provide effective relief for chronic nerve discomfort.
Mechanism of action
Amitriptyline inhibits the neuronal reuptake of serotonin and noradrenaline, increasing their concentrations in the central nervous system to modulate mood and pain pathways.
Amitriptyline Tablets
Designed to mitigate major depressive disorder and neuropathic pain, indicated to support mood regulation and provide effective relief for chronic nerve discomfort.
Editorial Notes
- Active ingredient(s): Amitriptyline
- Listed indication(s): Major Depressive Disorder, Neuropathic Pain
Usually available as
- 360 tablets - 10 mg945-10-mg-13870
- 270 tablets - 25 mg945-25-mg-11828
- 180 tablets - 50 mg945-50-mg-11833