Sofosbuvir Tablets
utilized to target chronic hepatitis c to address viral replication.
Strengths: 400mg
Where to Check Availability
Medicine details
- Conditions
- Alternative names
Sovaldi
- Therapeutic class
Direct-acting antiviral
- Pharmacological class
HCV NS5B polymerase inhibitor
- Contraindications
hypersensitivity
- Precautions and warnings
monitor liver function; not recommended in severe renal impairment
- Minor side effects
headache; nausea; fatigue
- Moderate side effects
insomnia; dizziness
- Serious side effects
bradycardia — requires immediate medical attention
- Dosage forms
Film-coated tablet
- Administration route
Oral use
- Patient summary
utilized to target chronic hepatitis c to address viral replication.
- Prescription status
POM
- Manufacturer
Gilead Sciences
- Onset Time
1–2 hours
- Duration
24 hours
- Storage instructions
Store below 30°C in the original container.
- Drug interactions
amiodarone; rifampicin; st. john's wort
- Age restrictions
Not indicated for use in children under 18 years.
Mechanism of action
Sofosbuvir works by inhibiting the NS5B protein, an enzyme essential for the hepatitis C virus to replicate its genetic material, thereby stopping the virus from multiplying within the body.
Pregnancy and breastfeeding
Pregnancy: not recommended unless clearly necessary. Breastfeeding: caution is advised, consult a specialist.
Sofosbuvir Tablets
utilized to target chronic hepatitis c to address viral replication.
Editorial Notes
- Active ingredient(s): Sofosbuvir
- Listed indication(s): Chronic Hepatitis C
Available option
- 28 tablets - 400 mg1340-400-mg-16166