Nitrofurantoin Tablets

This antibiotic is indicated to target urinary tract infections, developed to alleviate symptoms of cystitis and to support clearing bacterial bladder infections.

Strengths: 50 · 100mg

Medicine details

Alternative names

Macrobid; Macrodantin

Therapeutic class

Nitrofuran Antibiotic

Pharmacological class

Nitrofuran

Contraindications

renal impairment; glucose-6-phosphate dehydrogenase deficiency

Precautions and warnings

take with food to improve tolerance; may cause urine to change colour

Minor side effects

nausea; headache; flatulence

Moderate side effects

diarrhoea; dizziness

Dosage forms

Modified-release tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Various

Onset Time

2–4 hours

Duration

6–12 hours

Storage instructions

Store below 25°C, keep dry.

Drug interactions

Antacids; Probenecid

Age restrictions

Consult doctor for paediatric dosing.

Pregnancy and breastfeeding

Pregnancy: Use with caution, avoid at term. Breastfeeding: Generally safe.

Serious side effects

pulmonary fibrosis — requires immediate medical attention; hepatitis — requires immediate medical attention

Patient summary

This antibiotic is indicated to target urinary tract infections, developed to alleviate symptoms of cystitis and to support clearing bacterial bladder infections.

Mechanism of action

Nitrofurantoin is a bactericidal antibiotic that acts by damaging bacterial DNA. It is highly specific to the urinary tract due to its rapid excretion into urine upon oral administration.

Nitrofurantoin Tablets

This antibiotic is indicated to target urinary tract infections, developed to alleviate symptoms of cystitis and to support clearing bacterial bladder infections.

Editorial Notes

  • Active ingredient(s): Nitrofurantoin
  • Listed indication(s): Cystitis, Urinary Tract Infection

Usually available as

  • 90 tablets - 50 mg1174-50-mg-13908
  • 180 tablets - 100 mg1174-100-mg-13916