Trimethoprim Tablets
The product is developed to mitigate symptoms of bacterial infections when indicated by clinical testing.
Strengths: 400/80 · 800/160mg
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Medicine details
- Conditions
- Alternative names
Monotrim
- Therapeutic class
Dihydrofolate Reductase Inhibitor
- Pharmacological class
Diaminopyrimidine
- Known off-label uses
prostatitis
- Minor side effects
nausea; diarrhoea; skin rash
- Moderate side effects
pruritus; glossitis
- Dosage forms
Tablet
- Administration route
Oral use
- Prescription status
POM
- Manufacturer
Accord Healthcare
- Onset Time
1–2 hours
- Duration
3–7 days
- Storage instructions
Store in a cool, dry place away from light.
- Drug interactions
methotrexate; phenytoin; digoxin
- Age restrictions
Suitable for children and adults.
Contraindications
hypersensitivity to trimethoprim; severe renal impairment; folate deficiency anaemia
Precautions and warnings
complete the full course of treatment; maintain adequate fluid intake; monitor for signs of blood disorders
Serious side effects
blood dyscrasias — requires immediate medical attention; stevens-johnson syndrome — requires immediate medical attention
Patient summary
The product is developed to mitigate symptoms of bacterial infections when indicated by clinical testing.
Mechanism of action
Trimethoprim acts by competitively inhibiting bacterial dihydrofolate reductase, thereby preventing the synthesis of essential nucleic acids required for bacterial growth and replication.
Pregnancy and breastfeeding
Pregnancy: Use with caution, especially in first trimester. Breastfeeding: May be used with caution.
Trimethoprim Tablets
The product is developed to mitigate symptoms of bacterial infections when indicated by clinical testing.
Editorial Notes
- Active ingredient(s): Trimethoprim
- Listed indication(s): Urinary Tract Infection
Usually available as
- 360 tablets - 400/80 mg1148-400-80-mg-13617
- 360 tablets - 800/160 mg1148-800-160-mg-13623