Macrobid

indicated to target urinary tract infections by inhibiting bacterial growth.

Strengths: 50 · 100mg

Medicine details

Alternative names

Macrodantin

Therapeutic class

Urinary Anti-infective

Pharmacological class

Nitrofuran

Contraindications

renal impairment; hypersensitivity to nitrofurantoin

Precautions and warnings

may colour urine brown; monitor for pulmonary symptoms

Minor side effects

nausea; headache

Moderate side effects

diarrhoea; abdominal ache

Dosage forms

Prolonged-release capsule, hard

Administration route

Oral use

Patient summary

indicated to target urinary tract infections by inhibiting bacterial growth.

Prescription status

POM

Manufacturer

Alident

Onset Time

1–2 hours

Duration

12 hours

Storage instructions

Store below 25°C.

Drug interactions

magnesium trisilicate; probenecid

Age restrictions

Caution in elderly.

Pregnancy and breastfeeding

Use with caution. Avoid at term.

Serious side effects

pulmonary fibrosis — requires immediate medical attention; haepatotoxicity — requires immediate medical attention; peripheral neuropathy — requires immediate medical attention

Mechanism of action

Nitrofurantoin damages bacterial DNA in susceptible organisms, preventing growth within the urinary tract.

Macrobid

indicated to target urinary tract infections by inhibiting bacterial growth.

Editorial Notes

  • Active ingredient(s): Nitrofurantoin
  • Listed indication(s): Cystitis, Urinary Tract Infection

Usually available as

  • 180 tablets - 50 mg26-50-mg-3426
  • 180 tablets - 100 mg26-100-mg-3432