Misoprostol Tablets

Designed to target gastric acid production or support obstetric procedures, indicated to alleviate stomach ulcers or facilitate medical termination of pregnancy.

Strengths: 100 · 200mcg

Digestive Health icon Digestive Health Misoprostol icon Misoprostol

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Medicine details

Conditions
Alternative names

Cytotec

Therapeutic class

prostaglandin analogue

Pharmacological class

prostaglandin E1 analogue

Known off-label uses

cervical ripening

Contraindications

known hypersensitivity to prostaglandins

Precautions and warnings

do not use if pregnant (unless indicated for termination); monitor for diarrhoea

Minor side effects

diarrhoea; abdominal pain

Moderate side effects

nausea; flatulence

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Pfizer

Onset Time

30 minutes

Duration

3–6 hours

Storage instructions

Store below 30°C.

Drug interactions

antacids

Age restrictions

Adults only.

Serious side effects

uterine rupture — requires immediate medical attention; anaphylaxis — requires immediate medical attention

Patient summary

Designed to target gastric acid production or support obstetric procedures, indicated to alleviate stomach ulcers or facilitate medical termination of pregnancy.

Mechanism of action

Misoprostol is a synthetic prostaglandin E1 analogue. It replaces protective prostaglandins in the stomach, reducing acid secretion and increasing mucous production. In obstetric use, it acts on the cervix and uterus to cause contraction and softening.

Pregnancy and breastfeeding

Pregnancy: causes uterine contractions; contraindicated unless used for indicated pregnancy procedures.

Misoprostol Tablets

Designed to target gastric acid production or support obstetric procedures, indicated to alleviate stomach ulcers or facilitate medical termination of pregnancy.

Editorial Notes

  • Active ingredient(s): Misoprostol
  • Listed indication(s): Peptic Ulcer Prophylaxis, Medical Termination of Pregnancy

Usually available as

  • 90 tablets - 100 mcg1162-100-mcg-17393
  • 60 tablets - 200 mcg1162-200-mcg-13731