Asacol

Indicated for ulcerative colitis and formulated to mitigate inflammation.

Strengths: 400mg

Medicine details

Alternative names

Octasa; Salofalk; Mezavant

Therapeutic class

Aminosalicylate

Pharmacological class

Anti-inflammatory

Known off-label uses

crohn's disease

Minor side effects

headache; nausea; diarrhoea

Moderate side effects

rash; abdominal pain; arthralgia

Dosage forms

Gastro-resistant tablet

Administration route

Oral use

Patient summary

Indicated for ulcerative colitis and formulated to mitigate inflammation.

Prescription status

POM

Manufacturer

Tillotts Pharma

Onset Time

1–2 weeks

Duration

Ongoing treatment

Storage instructions

Store below 25°C in a dry place.

Drug interactions

azathioprine; mercaptopurine

Age restrictions

Consult physician for use in children.

Pregnancy and breastfeeding

Discuss with doctor; generally considered safe but monitoring advised.

Contraindications

hypersensitivity to salicylates; severe renal impairment; severe hepatic impairment

Precautions and warnings

monitor renal function periodically; use with care in patients with active peptic ulcer

Serious side effects

nephrotoxicity — requires immediate medical attention; blood dyscrasias — requires immediate medical attention

Mechanism of action

Mesalazine exerts a local anti-inflammatory effect on the intestinal mucosa, likely by inhibiting cyclooxygenase and lipoxygenase, thereby decreasing the production of prostaglandins and leukotrienes.

Asacol

Indicated for ulcerative colitis and formulated to mitigate inflammation.

Editorial Notes

  • Active ingredient(s): Mesalazine
  • Listed indication(s): Ulcerative Colitis

Available option

  • 90 tablets - 400 mg370-400-mg-2100