Remeron

This medication is indicated for major depressive disorder and utilized to manage associated symptoms such as sleep disturbance and loss of appetite.

Strengths: 7.5 · 15 · 30mg

Antidepressants icon Antidepressants Mirtazapine icon Mirtazapine

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Medicine details

Conditions
Alternative names

Zispin

Therapeutic class

Tetracyclic Antidepressant

Pharmacological class

Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)

Known off-label uses

generalized anxiety disorder; insomnia

Contraindications

hypersensitivity to mirtazapine; concurrent use of MAO inhibitors

Minor side effects

drowsiness; increased appetite; weight gain; dry mouth

Moderate side effects

dizziness; oedema

Dosage forms

Tablet

Administration route

Oral use

Prescription status

POM

Manufacturer

Organon

Onset Time

1–2 weeks

Duration

6–12 months

Storage instructions

Store below 30°C in the original packaging.

Drug interactions

Alcohol; Benzodiazepines; MAO inhibitors

Age restrictions

Caution in elderly patients.

Precautions and warnings

may impair ability to drive or operate machinery; monitor for worsening depression or suicidal ideation

Serious side effects

agranulocytosis — requires immediate medical attention; seizures — requires immediate medical attention

Patient summary

This medication is indicated for major depressive disorder and utilized to manage associated symptoms such as sleep disturbance and loss of appetite.

Mechanism of action

Mirtazapine enhances central noradrenergic and serotonergic activity by antagonizing alpha-2-adrenergic receptors and serotonin 5-HT2 and 5-HT3 receptors. This mechanism leads to an increased release of norepinephrine and serotonin.

Pregnancy and breastfeeding

Pregnancy: use only if benefit outweighs risk. Breastfeeding: discuss with your physician.

Remeron

This medication is indicated for major depressive disorder and utilized to manage associated symptoms such as sleep disturbance and loss of appetite.

Editorial Notes

  • Active ingredient(s): Mirtazapine
  • Listed indication(s): Major Depressive Disorder

Usually available as

  • 180 tablets - 7.5 mg96-7-5-mg-17371
  • 120 tablets - 15 mg96-15-mg-4053
  • 60 tablets - 30 mg96-30-mg-4057